BG大游集团

      BG大游集团 /诊断试剂 /热门肿瘤标志物 /TMB /tTMB-P1(5.37) Reference Standard

      tTMB-P1(5.37) Reference Standard

      CBP80001-1

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      I. Background

      Tumor mutational burden (TMB) shows great promise as a biomarker for immuno-oncology (I-O) therapy response, but progress is hindered by the lack of a standardized TMB measurement by targeted NGS panels, and an absence of TMB reference materials.

       

      Sample ID

      Cat.No.

      Background

      Assay

      Comments

      DC198N0153

      CBP80001-1N

      B lymphoblast, Female

      500x WES

      Same individual

       

      DC198N0152

      CBP80001-1T

      Ductal breast carcinoma, Female

      500x WES

      IDT xGenExome Research Panel v1.0捕获,Target Region 39M, Probe Region 51M, CDS Region 33.52M;
      HiSeq X-TEN,af选择0.02 cut off,再过滤。
      DC198N0152 is 100% Tumor sample.

       

       

       

      Cut off =2%

      Cut off =3%

      Cut off =4%

      Cut off =5%

      Mutation Number

      180

      172

      168

      166

      TMB value

      5.37

      5.13

      5.01

      4.95 


      计算数据下载:DC198N0152.tmb


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